Formal Learning Objectives of the Ph.D. Program

BCH 223

Physical Biochemistry (2 credits)

Faculty Member in charge:

Eric First, Ph.D., efirst@lsuhsc.edu

When course is offered: Spring, odd-numbered years

Description of course:

Discussions of physical and chemical techniques used in biochemistry to study macromolecular architecture and interactions.


BCH 271

Cell Signaling (1 credit)

Faculty Member in charge:                                                   

Lucy Robinson, Ph.D.,lrobin@lsuhsc.edu

When course is offered: Spring, odd-numbered years

Description of course:

A seminar/discussion course based on current literature. The theme (signaling pathway) covered by the course changes for each offering. The introduction of a topic by the instructor is followed by literature discussions led by students. Past examples of course themes include MAPK signaling in yeast, Drosophila and vertebrates, and two-component regulatory systems in prokaryotes and eukaryotes.


BCH 281

Molecular Mechanisms of Post-transcriptional Control (1 credit)

Faculty Member in charge:                                      

Ricky DeBenedetti, Ph.D., adeben@lsuhsc.edu

When course is offered: Fall, even-numbered years

Description of course:

This course is designed to introduce the student to modern concepts and techniques in the biochemistry and molecular biology of posttranscriptional control.  This process will occur through reading and discussing key papers in the literature and writing a short proposal pertaining to a testable hypothesis.  The papers selected will be of two kinds: landmark papers which have revolutionized the thinking in a particular area of posttranscriptional control, and recent representative papers which deal with the most modern topics and techniques.


BCH 283

Molecular Mechanisms of Transcriptional Control (1 credit)

Faculty Member in charge:                                        

David S. Gross, Ph.D., dgross@lsuhsc.edu

When course is offered: Spring, odd-numbered years

Description of course

Literature-based course covering the role of promoter-specific activators and repressors, the nature and role of the general transcriptional machinery, and the role of nucleosomes and higher order chromatin structures in regulating transcription.


BCH 286

Classical and Molecular Genetics (1 credit) 

Faculty Member in charge:                                      

Kelly Tatchell, Ph.D., ktatch@lsuhsc.edu     

When course is offered: Fall, odd-numbered years

Description of course:

Emphasizes classical genetic methods as they apply to modem molecular biology. Course content relies on yeast as an experimental organism, although the intent is to teach genetic principles as they apply to eukaryotic organisms in general.


BCH 287

Applications of Spectroscopic Techniques to Biochemical Problems (1 credit)

Faculty Member in charge:  

Stephan Witt, Ph.D., switt1@lsuhsc.edu

When course is offered: Fall, odd-numbered years

Description of course:

Emphasizes the principles of well-established methods, such as fluorescence spectroscopy and surface plasmon resonance spectroscopy, and their applications to biochemical problems.


BCH 290
                           

Introduction to Bioinformatics (3 credits)

Faculty Member in charge:      

Eric A. First, Ph.D., efirst@lsuhsc.edu

When course is offered: Fall, odd-numbered years

Description of course

This course is designed to provide an introduction to the computational and biological concepts and skills required for the field of bioinformatics. It provides an overview of the field and trains students in the use of some current bioinformatics programs. Some topics to be covered are biological databases, pairwise sequence alignment BLAST searching, analysis of gene expression data, proteomics, multiple sequence alignment, protein structure prediction, molecular phylogeny, genomic analysis, and PERL for bioinformatics. By the end of the course students should be able to search for novel genes of unkoown function, identify homologous proteins, and develop hypotheses regarding the function of novel genes. This course is cross-listed with CSC 490/690 at LSU-Shreveport (LSU-S students should contact mtrutsch@pilot.lsus.edu).