Research

Cancer Biology

ARRIGO DE BENEDETTI

Altered protein synthesis in solid tumors

SHILE HUANG

mTOR signaling in tumorigenesis and metastasis

HARI KOUL

Regulation of the Warburg effect in cancer; molecular targets in prostate and pancreatic cancer

NANCY LEIDENHEIMER

Role of GABA shunt in cancre cell metabolic reprogramming

SERGEY SLEPENKOV

Anticancer activity of the small molecule tetrandrine and its interaction with protein targets in prostate cancer cells

STEPHAN N. WITT

Alpha Synuclein and melanoma

XIUPING YU

Prostate cancer and prostatic disease

Cell Cycle and Cell Signaling

ARRIGO DE BENDETTI

Gene expression; radioresistance by the protein kinase Tousled; gene therapy

SHILE HUANG

mTOR signaling in tumorigensis and metastasis

BRENT REED

Functions of GLUT1CBP (GIPC), a myosin VI adapter protein

LUCY ROBINSON


Control of cell growth and division, protein phosphorylation, vesicular trafficking, and yeast genetics.

GULSHAN SUNAVALA-DOSSABHOY

Genotoxin-mediated DNA damage and repair, and salivary function

Enzymes, Proteins,  and Protein Engineering

ERIC FIRST


Aminoacylation of tRNA; expansion of the genetic code; Charcot-Marie-Tooth disorder; enzyme catalysis; protein engineering

HARI KOUL

Mechanisms of oxalate nephrotoxicity

NANCY LEIDENHEIMER

Bioenergetics of the GABA shunt, A TCA cycle bypass mechanism

GULSHAN SUNAVALA-DOSSABHOY

Protein and small molecule therapies to supress radiation damage to non-cancerous tissues

KELLY TATCHELL

Type 1 protein phosphatase (PP1) in the yeast Saccharomyces cerevisiae

STEPHAN N. WITT

Vessicle trafficking and molecular bases of diseases


Epigenetics and Transcription 

DAVID S. GROSS

Regulation of gene expression; chromosome conformation of genes and their 3D nuclear organization; transcriptional response to heat shock


Neurobiology and Neurodegeneration

SHILE HUANG

Nueronal apoptosis

NANCY LEIDENHEIMER

Function, trafficking and degradtion of gamma-aminubutyric (GABA) receptors

STEPHAN N. WITT

Alpha Synuclein and Parkinson's disease